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Prodrug of tenofovir works well in the presence of some NRTI resistance

Treatment-experienced individuals who have one or two thymidine analogue-associated resistance mutations still experience a significant reduction in HIV viral load if treated with tenofovir disoproxil

Published
02 May 2004
By
Michael Carter
Boosted PIs superior to no PIs as salvage therapy in highly PI-experienced

A small Italian study comparing boosted protease inhibitor (PI) and PI-sparing salvage regimens in the highly PI-experienced has found the former superior in preserving CD4

Published
24 April 2004
By
Edwin J. Bernard
Can atazanavir reverse body fat changes?

Switching to the protease inhibitor atazanavir (Reyataz) can result in rapid improvement in lipodystrophy-associated body shape abnormalities and blood lipids, according to a short series

Published
08 April 2004
By
Michael Carter
Meta-analysis finds PI-based HAART better than NNRTI regimens in NRTI experienced

Protease inhibitor (PI)-based highly active antiretroviral therapy (HAART) regimens are superior to non-nucleoside reverse transcriptase inhibitor (NNRTI)-based triple combinations, according to a meta-analysis of 14

Published
30 January 2004
By
Michael Carter
More bad news on tenofovir/abacavir/3TC

Replacing a suppressive anti-HIV regimen with tenofovir/abacavir/3TC is a risky strategy according to a small, retrospective study published in The Lancet this week. Dutch researchers identified

Published
16 December 2003
By
Megan Nicholson
Minority can have CD4 rises and no illness for more than 3 years after treatment failure

People with a stable low detectable viral load who continue with existing treatment continue to have rising CD4 cell counts and no clinical progression for

Published
11 December 2003
By
Edwin J. Bernard
Gastrointestinal side-effects lead one in eight to change HAART regimen in first year of treatment

Over 50% of patients taking anti-HIV treatments for the first time will change or stop taking their drugs in the first year of therapy, often

Published
27 November 2003
By
Michael Carter
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